Medication for Weight Loss on Prescription

Medication for weight loss
December 9, 2021 0 Comments

It is necessary for diet pills to be able to block the absorption of fat from meals via the small intestine in order for them to be beneficial. Some drugs may have the extra effect of improving the body’s metabolism or lowering appetite in addition to their primary effects.

Lots of individuals have misconceptions about diet pills and how they function, and it is important to debunk such misconceptions as soon as possible. For example, many people assume that diet pills allow a person to lose weight by increasing their metabolism and speeding up their metabolism, which is not true. Taking medicine or supplement will not, however, speed up a person’s metabolism, since this is not possible with medications or supplements.

An overview of how diet pills work is given in the next section:

Diet pills are now widely accessible in a variety of settings, including stores, the internet, and broadcast television. But, more specifically, how do they work? Many different types of diet pills are available; nevertheless, caffeine, amino acids (which help you feel fuller for longer periods of time), and herbal extracts are among the most often included in the majority of them (which make you sweat more). All of these components have one thing in common: they are unable of assisting you in losing weight on their own, and they are incapable of assisting you in losing weight rapidly.

Reduced calorie intake combined with increased physical activity are the cornerstones of long-term weight loss success. Prescription weight-loss medications may be beneficial for some people who are overweight or obese.

If you are taking these medications, you will still need to pay attention to your diet and physical activity, and they are not recommended for everyone because of their side effects.

Patients with a body mass index (BMI) of 30 or higher, or a BMI of at least 27 who have a disease that may be linked to their weight, such as type 2 diabetes or high blood pressure, are more likely to be prescribed weight-loss medications.

The Food and Drug Administration (FDA) granted approval for the use of the medication semaglutide (Wegovy) in the treatment of obesity in 2021. Among the weight-loss drugs that have been in use for a longer length of time is liraglutide (Saxenda), naltrexone-bupropion (Contrave), orlistat (Alli, Xenical), phentermine (Adipex-P, Ionamin, Pro-Fast), phentermine-topiramate (Adipex-P, Ionamin, Pro-Fast), phen (Qsymia).

Before acquiring a prescription for a weight-loss medicine, tell your doctor about any medical conditions you are experiencing. Factors evaluated include any allergies or diseases you may be suffering from; drugs or supplements you may be taking (even if they are herbal or natural); and if you are pregnant, breastfeeding, or planning to become pregnant in the near future, among other things.

 

Dietary Supplements to Lose WeightDietary Supplements to Help You Lose Weight

Liraglutide

Diabetes is treated using liraglutide, a medicine that is available over the counter (Saxenda)

The term refers to a kind of drug that is used to assist persons with type 2 diabetes decrease their blood sugar levels.

Liraglutide is a medication that is classified as a glucagon-like peptide-1 (GLP-1) receptor agonist, which is a kind of diabetes medication. It works by boosting the synthesis of insulin in the body and assisting it in performing its functions more effectively. As well as being used to treat type 2 diabetes, liraglutide is also used to maintain diabetes mellitus in those who have type 1 diabetes.

The following is an explanation of how it works: Liraglutide is a potent form of the type 2 diabetes drug Victoza that is already available. This medicine works by simulating the production of a hormone by the gut that signals to the brain when your stomach is completely full.

Liraglutide was licensed by the Food and Drug Administration (FDA) for the treatment of type 2 diabetes for the first time in 2007.

It is safe to use for a longer period of time, but what about long-term usage? Yes.

Symptoms and Side Consequences

It is possible to have negative side effects such as nausea, vomiting, diarrhea, constipation, low blood pressure, and increased hunger when using this medication. It is possible that these drugs may induce unpleasant side effects such as elevated heart rate, pancreatitis, gallstone illness, renal difficulties, and suicidal thoughts. Although the medication liraglutide has been demonstrated to produce thyroid tumors in animal studies, it is not known whether or not it will cause thyroid cancer in people at this point.

In certain persons, liraglutide may cause heart failure as a consequence of an enlarged heart or as a result of other conditions such as uncontrolled high blood pressure or congestive heart failure. There is no indication of any long-term repercussions on the heart in people who have never had a history of cardiovascular disease. The risks associated with taking cholesterol-lowering medication are minimal in the case of a healthy individual.

According to FDA guidelines, if you do not lose 4 percent of your body weight after 16 weeks of using Liraglutide, your doctor may advise you to stop taking the medicine since it is unlikely to work for you. Liraglutide is a prescription weight-loss medication.

Naltrexone HCl and Bupropion

Naltrexone HCl and bupropion are two drugs that are utilized in the treatment of substance abuse disorders (Contrave)

Contrave is a pharmaceutical that has been the subject of controversy since it is a combination of two FDA-approved drugs, naltrexone and bupropion, that is delivered in an extended-release form. Naltrexone is a medicine that has been approved by the FDA for the treatment of alcohol and opiate addiction, among other conditions. Bupropion is a medicine that has been approved for the treatment of depression, seasonal affective disorder, and to aid patients in their efforts to stop tobacco use.

It is safe to use for a longer period of time, but what about long-term usage? Yes.

Symptoms and Side Consequences

The most common side effects of this drug include nausea, constipation, headache, vomiting, dizziness, insomnia, and dry mouth, which are all caused by the medication. According to a boxed warning on the Contrave package insert, bupropion has been associated with suicidal thoughts and behaviors. Aside from that, the warning indicates that substantial neuropsychiatric problems have been associated with the use of bupropion. Contrave has the potential to cause seizures and, as a result, should not be administered to anyone who has seizure disorders. Aside from that, there is a possibility that the medication may boost blood pressure and heart rate.

As a result of these recommendations from the FDA, if you have not lost 5 percent of your body weight after 12 weeks of using Contrave, your doctor may suggest you stop taking the drug since it is unlikely to succeed for your particular situation.

 

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OrlistatOrlistat

Orlistat is a medicine that aids in the loss of excess weight (Xenical)

Orlistat is a prescription weight-loss medication that has been on the market since 1999 and is FDA-approved. As a result, about one-quarter of dietary fat is prevented from being absorbed by the body, resulting in decreased fat accumulation and weight reduction in certain people.

Takuji Ishizaki, a Japanese pharmaceutical firm researcher, developed it in 1989 and licensed it to Takeda Pharmaceutical Business Limited, a Japanese pharmaceutical company, in 1992 for use outside of Japan.

If you are overweight or obese and have at least one medical condition such as type 2 diabetes, high cholesterol, or high blood pressure, orlistat, also known as Xenical and Alli, is available as a prescription drug and an over-the-counter (OTC) medication. The medicine works by preventing the absorption of certain fats from meals consumed in the diet, hence assisting patients in losing weight.

The way it works is that it inhibits your body from absorbing around one-third of the fat that you ingest.

The medicine Xenical is prescribed by a doctor when the patient has been prescribed orlistat. In the United States, it is known as Alli if it is purchased without a prescription and contains half the dose of Xenical.

It is safe to use for a longer period of time, but what about long-term usage? Yes.

It is likely that this medicine can cause abdominal pains, gas, spilling oily feces, having more bowel movements, and not being able to control bowel movements as a side effect.

In most cases, these side effects are minor and only endure for a short length of time. However, if you eat a lot of high-fat meals, your symptoms may deteriorate much worse.

People on orlistat have been reported to have had rare cases of substantial liver damage; however, it is not known whether the medication was the cause of the problems in these individuals.

Customer reports of gastrointestinal issues such as oily discharge, steatorrhea (fatty stools), fecal urgency, urinary incontinence, flatulence, and loose stools have been documented after beginning treatment with orlistat.

Important information to remember before taking orlistat is that you should be on a low-fat diet (with fewer than 30% of your daily calories coming from fat) before beginning treatment.

Taking a multivitamin at least 2 hours before or after taking orlistat is also recommended since the medication makes it temporarily more difficult for your body to absorb vitamins A, D, E, and K. Also, consult your doctor before starting or stopping orlistat. Taking a multivitamin at least 2 hours before or after taking orlistat is also recommended.

Orlistat is the only medication in its class to have been approved by the Food and Drug Administration (FDA) in the United States. Suppressing your appetite is the mechanism by which all other prescription weight-loss drugs, including the ones mentioned here, operate.

 

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PhenterminePhentermine

Phentermine was initially created in the 1950s and was used to treat obesity during the time of its development.

Phentermine is a prescription medication that is often administered for the purpose of weight reduction. In addition to being an appetite suppressant, it is also a central nervous system stimulant that may be taken in conjunction with other forms of weight-loss therapy.

In its interactions with the central nervous system, phentermine raises the levels of dopamine and serotonin in the brain, which improves mood while also suppressing appetite. In turn, this may lead to increased energy and decreased hunger, as well as a reduction in emotions of despair or worry.

It is safe to use for a longer period of time, but what about long-term usage? No. It is only permitted to be used for a certain length of time at a time (a few weeks).

High blood pressure or heart palpitations, restlessness, dizziness, tremor, sleepiness, shortness of breath, chest tightness, and trouble doing activities that you were previously able to complete without difficulty are all possible side effects of this medication.

The less significant side effects of this drug include dry mouth, foul taste, diarrhea, constipation, and vomiting, to name a few examples.

There is a risk of becoming dependent on the medicine, just as there is a risk of becoming dependent on certain other appetite suppressants.

It is not suggested to take it late in the evening since it has the potential to make you sleepless.

If you have diabetes and are on insulin, you should tell your doctor before taking phentermine since your insulin dose may need to be altered as a result of the medication.

When it comes to heart disease, stroke, congestive heart failure, or uncontrolled high blood pressure, it is best to avoid using phentermine. As a precaution, you should not take it when you have glaucoma, hyperthyroidism, or a history of drug abuse, or while expecting, or while nursing, a child or an infant.

What else you should know: Phentermine is classed as amphetamine, which means it is addictive. These stimulant drugs are classed as “controlled substances,” since they have the potential for addiction or abuse. This means that they need a specific kind of prescription.

 

Phentermine and Topiramate

Phentermine and topiramate are both appetite suppressant drugs that are used to aid in the weight loss of individuals.

Phentermine is a stimulant that is also used to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents (ADHD). Anticonvulsant medication sold under the trade name Topamax is used to treat seizures as well as prevent migraine headaches. It is also used to treat and prevent migraine headaches. As well as treating bipolar disorder and alcoholism, it may also be effective in the treatment of other illnesses. Short-term weight loss of 5 percent or more is possible with both drugs; however, there is inadequate evidence to support their long-term usefulness for this purpose in the current literature.

Phentermine and topiramate are currently being studied to determine their specific mechanism of action; nevertheless, it is believed that they may increase the synthesis of satiety hormones or decrease hunger signals from the brain or stomach.

This class of drugs causes a rise in energy expenditure because they activate the sympathetic nervous system, which in turn raises the metabolic rate. As a crucial component of the autonomic or involuntary nervous system, which is responsible for sending instructions to multiple organs and tissues throughout the body, the sympathetic nervous system (SNS) is responsible for a variety of functions.

phentermine and topiramate are combined as the prescription medicine Qsymia, which helps people lose weight by suppressing their appetites while also treating their seizure and migraine symptoms. There are many ways that topiramate helps you lose weight, including making you feel filled for longer periods of time, making meals tastes less attractive, and boosting the number of calories you burn.

It is safe to use for a longer period of time, but what about long-term usage? Yes. If Qsymia is used with phentermine and topiramate, the concentrations of these drugs are much lower than if these medications are taken alone.

The effects on the body are as follows: tingling in the hands and feet, disorientation, altered taste perception, insomnia, constipation, and a dry mouth are the most common side effects.

Some major side effects include birth abnormalities (such as cleft lip and palate), elevated heart rate, suicidal thoughts or behaviors, and eye problems that, if left untreated, might result in irreparable vision loss.

A pregnancy test should be conducted before commencing therapy with Qsymia, and women who are considering conception should continue to use birth control and undergo monthly pregnancy tests while on the drug.

If you suffer from glaucoma, hyperthyroidism, cardiovascular illness, or a stroke, you should also avoid using Qsymia for the time being. You should get your heart tested on a regular basis when you first begin taking the medicine or when you raise the dose.

If you have not lost at least 3 percent of your body weight after 12 weeks on Qsymia, the FDA recommends that you either stop taking it or that your doctor increase the dose for the next 12 weeks — and if that does not work, the FDA recommends that you gradually stop taking it completely.

 

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Semaglutide

Semaglutide is an anti-nausea and anti-vomiting drug used to treat nausea and vomiting (Wegovy)

Essentially, Semaglutide works by replicating an intestinal hormone that increases insulin synthesis, so lowering appetite, and increasing the sensation of being satisfied after eating.

Semaglutide was the first medication to be approved for use as a treatment for type 2 diabetes, and it is now sold under the brand names Ozempic and Rybelsus for this use. In accordance with what Wegovy has previously indicated, it is meant only for the treatment of obesity.

It is safe to use for a longer period of time, but what about long-term usage? Yes.

Some of the negative effects of this drug include abdominal pains, constipation, vomiting, passing gas, headache, drowsiness, and gastro reflux.

In most cases, these side effects are minor and only endure for a short length of time.

It has been claimed that renal problems, as well as cloudy vision, have occurred in rare situations. Certain occurrences of Semaglutide-induced pancreatitis have been linked to a link between Semaglutide and pancreatic disease (pancreatitis). If you experience any of the symptoms of pancreatitis, which include severe stomach/abdominal pain, nausea/vomiting that does not stop, and vomiting that does not stop, get medical assistance as soon as possible.

Furthermore, according to the existing research, you would need to take Semaglutide for the rest of your life in order to maintain a healthy weight and prevent diabetes. Stopping taking it suddenly may result in you regaining most of the weight you have already lost.

You should also eat a low-calorie diet and participate in regular physical exercise to sustain your weight loss.

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